WebJul 7, 2016 · GSK-3 differentially regulates 4EBP1 and S6RP phosphorylation in ACHN cells. a Changes in the phosphorylation levels of 4EBP1 and S6RP over time after treatment of AR-A014418 (25 μM) or rapamycin ... WebDec 18, 2024 · Scoring of phospho-4EBP1 immunolabeling was performed as follows: each tumor was evaluated in a tissue microarray for positive or negative staining, and assigned a qualitative score based on whether there was low, focal staining (staining in less than 50% of the tumor cells), intermediate staining (weak staining in more than 50% of the cells ...
Immunohistochemical Assessment of Phosphorylated mTORC1 …
WebPhospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. … WebApr 14, 2024 · Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of rapamycin (mTOR) inhibitor rapamycin suppressed orofacial formalin injection-induced nociception; however, the … how do skates and rays differ from sharks
Recombinant Anti-eIF4EBP1 (phospho T70) antibody [EPR654(2)A…
WebThe Phospho-4EBP1 (Thr37/46) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific … WebJan 2, 2024 · Here we demonstrate that rapamycin-insensitive mTORC1 signaling via 4E-BP1 is a critical pathway for TGF-β 1 stimulated collagen synthesis in human lung fibroblasts, whereas canonical PI3K/Akt... WebThe ER is the main organelle for calcium (Ca 2+) storage in cells.Its physiological function is closely related to Ca 2+ homeostasis (Wong et al., 1993).To investigate the effect of As 3+ /Se 4+ combination on ER function, this study pretreated cells with ERS inducer thapsigargin (TG) and ERS inhibitor 2-aminoethoxydiphenyl borate (2-APB), followed by Fluo-3-AM and … how do six month cds work