Bioactive benzofuran derivatives: a review
WebThe benzofuran nucleus is present in a huge number of bioactive natural and synthetic compounds. Benzofuran derivatives have potent applications in pharmaceuticals, … WebAug 16, 2013 · Introduction: Benzofuran moiety constitutes the core of several interesting pharmacologically active natural products. Benzofurans are among feasible potent active inhibitors against many diseases, viruses, microbes, fungus and enzymes. Several series of therapeutically important synthetic and naturally occurring benzofuran-containing …
Bioactive benzofuran derivatives: a review
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WebAlso, this study systematically provides a comprehensive report on current developments in benzofuran-based compounds as antioxidant agents and is also helpful for the … WebNov 1, 2015 · Bioactive Benzofuran derivatives: A review. Eur J Med Chem 2015;97:483-504. 10. ... benzofuran derivatives (review). Chem Hetero Comp 1997;33: 1245-58. 14. Sidhu PS. Review: One-pot synthesis ...
WebNov 22, 2014 · A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives. Chand K, Rajeshwari, Hiremathad A, Singh M, Santos MA, Keri RS. Pharmacol Rep, 69(2):281-295, 18 Nov 2016 Cited by: 17 articles PMID: 28171830. Review WebNov 18, 2016 · This review discusses the structure–activity relationship (SAR) of several benzofuran derivatives in order to elucidate the possible substitution alternatives and …
WebAMP-activated protein kinase (AMPK) has been proposed as a therapeutic target for the treatment of metabolic syndrome including obesity and type-2 diabetes. The bioassay-guided fractionation of an EtOAc-soluble extract of the stem bark of Erythrina abyssinica led to the isolation of a new coumestan, erythribyssin N (1), and two new benzofurans, …
WebNov 22, 2014 · A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives. Chand K, Rajeshwari, Hiremathad A, Singh M, Santos …
WebMar 10, 2024 · By screening bioactive molecules similar to “SalC” with SwissSimilarity, a series of benzofuran derivatives were found in the ChEMB database . These compounds were then exported to SwissADME and docked with JAK (PDB: 6DBN), and the compounds with drug-like properties and JAK affinity potential are recorded in Figure 7 and Table 4 . iper carrefour paviaWebJun 5, 2015 · The present review will provide an insight on lead design-developments of the decade, clin … Benzofuran core is a highly versatile, presents in many important natural … iperceramica outlet romaWebFor the benefit of natural product-based drug discovery, available sources of these derivatives, extraction process and reported biological activities have also been outlined in this review. Keywords: Benzofuran derivatives , drug and non-drug application , metal catalysts , ring-closure , cytotoxicity , syntheticstrategies. iperc foundationWebMar 11, 2014 · Aimed at developing novel fungicides for relieving the ever-increasing pressure of agricultural production caused by phytopathogenic fungi, 28 new hydrazone derivatives of carabrone, a natural bioactive sesquisterpene, in three types were designed, synthesized and their antifungal activities against Botrytis cinerea and Colletotrichum … open wooden shelves for classroomWebBackground: The 2-substituted benzofuran framework has attracted enormous attention due to its presence in a range of bioactive compounds and natural products. While various methods for the synthesis of 2- substituted benzofuran derivatives are known, several of them suffer from certain drawbacks. Objective: The main objective of this work was to … iper carrefour polleinAbstract. In nature's collection of biologically active heterocycles, … open wood shelves in kitchenWebIn nature's collection of biologically active heterocycles, benzofuran derivatives constitute a major group. The broad spectrum of pharmacological activity in individual benzofurans … i perchance hereafter shall think meet